Peptide Registry

TUDCA

$59.00

  • Contents: TUDCA (Tauroursodeoxycholic acid; taurine-conjugated secondary bile acid)
  • Format: Encapsulated solid
  • Appearance: White to off-white solid
  • Purity: >99%
Quantity Discount Price
1 - 3 - $59.00
4 - 7 10% $53.10
8 + 18% $48.38
SKU: N/A Category: Brand:

Description

TUDCA (tauroursodeoxycholic acid) is an endogenous secondary bile acid formed by taurine conjugation of ursodeoxycholic acid in the liver. It functions as an endoplasmic reticulum stress inhibitor, mitochondrial membrane stabilizer, and anti-apoptotic signaling modulator across hepatocellular, neuronal, and retinal cell populations, acting through suppression of the unfolded protein response (UPR) and stabilization of the mitochondrial permeability transition pore (mPTP). Its well-established oral bioavailability and natural role as a bile acid undergoing enterohepatic circulation make capsule format the standard and mechanistically appropriate delivery method for TUDCA in preclinical research models.

Storage and Handling

Store in a cool, dry place away from heat, moisture, and direct light. Keep container tightly sealed when not in use. TUDCA is stable under standard ambient storage conditions; refer to the lot-specific certificate of analysis for specific requirements.

Compliance Notice

TUDCA capsules are for laboratory research use only. They are not for human or veterinary use and carry no therapeutic, diagnostic, or clinical indication. FDA has not evaluated this product. By purchasing this product, the buyer confirms that they will follow appropriate institutional safety procedures and use it exclusively for controlled research.

Frequently Asked Questions

Why is capsule format the standard format for TUDCA research?

TUDCA is a bile acid derivative with well-established oral bioavailability and a natural role in hepatobiliary physiology through enterohepatic circulation. As an endogenous metabolite absorbed efficiently through the intestinal bile acid transport system, oral capsule format is the mechanistically appropriate and most practical delivery method for preclinical research models.

What research contexts is TUDCA used for beyond hepatocellular biology?

TUDCA's ER stress inhibition and mPTP stabilization mechanisms are relevant across multiple cell populations. Neuronal and retinal cell models use it for studying how ER stress modulation affects cell survival signaling. Researchers studying proteostasis, UPR regulation, and mitochondrial permeability dynamics in any cell type where ER stress is an active variable may use TUDCA as a defined ER stress inhibitor reference compound.