Peptide Registry

Methylene Blue

$69.00

  • Contents: Methylene Blue (3,7-bis(dimethylamino)phenothiazin-5-ium chloride; phenothiazine dye)
  • Format: Encapsulated solid
  • Appearance: Blue crystalline solid
  • Purity: >99%
Quantity Discount Price
1 - 3 - $69.00
4 - 7 10% $62.10
8 + 18% $56.58
SKU: N/A Category: Brand:

Description

Methylene Blue is a mitochondrial electron carrier and redox-cycling compound that functions as an alternative electron acceptor in the electron transport chain, accepting electrons from NADH and donating them to cytochrome c independently of complex I-III. This alternative electron transport pathway is studied in models examining mitochondrial bioenergetics under conditions of ETC dysfunction, neuroprotective signaling, and cellular redox state modulation. Its oral bioavailability and well-characterized redox cycling properties make capsule format the standard delivery method for Methylene Blue in preclinical research models.

Storage and Handling

Store in a cool, dry place away from heat, moisture, and direct light. Keep container tightly sealed when not in use. The characteristic blue color is intrinsic to oxidized Methylene Blue and is not an indicator of contamination. Note that it stains surfaces and handling materials; use appropriate precautions during capsule handling and analytical work.

Compliance Notice

Methylene Blue capsules are for laboratory research use only. They are not for human or veterinary use and carry no therapeutic, diagnostic, or clinical indication. FDA has not evaluated this product. By purchasing this product, the buyer confirms that they will follow appropriate institutional safety procedures and use it exclusively for controlled research.

Frequently Asked Questions

Why is Methylene Blue suited to oral capsule format in research?

Methylene Blue is a small organic molecule with well-documented oral bioavailability. It is absorbed through the gastrointestinal tract and distributes readily into tissues including the CNS due to its lipophilic character in its reduced leuco-methylene blue form. This oral bioavailability makes capsule format the mechanistically appropriate delivery method for preclinical research models.

What does the blue color of Methylene Blue capsules indicate?

The blue color is intrinsic to Methylene Blue in its oxidized form and is expected. Methylene Blue cycles between its oxidized blue form and its reduced colorless leuco-methylene blue form during redox reactions — this redox cycling is the basis of its mitochondrial electron transport research mechanism. The color confirms compound identity and integrity.