Peptide Registry

KPV (Capsules)

$99.00

  • Contents: KPV (Lys-Pro-Val; C-terminal alpha-MSH tripeptide)
  • Format: Encapsulated solid
  • Appearance: White to off-white solid
  • Purity: >99%
Quantity Discount Price
1 - 3 - $99.00
4 - 7 10% $89.10
8 + 18% $81.18
SKU: N/A Category: Brand:

Description

KPV is the C-terminal alpha-MSH tripeptide that suppresses NF-kB transcriptional activity through receptor-independent intracellular IkBa stabilization and p65 nuclear translocation inhibition. KPV capsules are particularly well-suited among peptide research compounds because of their documented PepT1 di/tripeptide transporter-mediated intestinal epithelial uptake, making oral delivery a biologically relevant experimental condition rather than simply a handling convenience. Researchers studying NF-kB suppression in gastrointestinal epithelial models use the capsule format to leverage this transporter-specific oral uptake mechanism.

Storage and Handling

Store in a cool, dry place away from heat, moisture, and direct light. Keep container tightly sealed when not in use. Refer to the lot-specific certificate of analysis for recommended storage conditions.

Compliance Notice

KPV capsules are for laboratory research use only. They are not for human or veterinary use and carry no therapeutic, diagnostic, or clinical indication. This product has not been evaluated by the FDA. By purchasing this product, the buyer confirms that they will follow appropriate institutional safety procedures and use it exclusively for controlled research.

Frequently Asked Questions

Why is KPV particularly suited to capsule format among peptide research compounds?

KPV is recognized as a PepT1 di/tripeptide transporter substrate on intestinal epithelial cells. This transporter-mediated uptake mechanism makes oral delivery a biologically relevant experimental condition for KPV specifically, unlike larger peptides that face significant gastric degradation and lack PepT1 substrate compatibility.

How does the oral KPV research context differ from parenteral protocols?

Oral KPV research examines PepT1-mediated intestinal uptake and downstream NF-kB suppression in the gastrointestinal epithelial context. Parenteral protocols bypass intestinal uptake and distribute the compound systemically. The two routes address different research questions and should be selected based on the tissue biology the study targets.